FERRUM +
complex anti-anemia agent that increases the level of hemoglobin
FERRUM +
complex anti-anemia agent that increases the level of hemoglobin
10 ml |
50 ml |
100 ml |
200 ml |
250 ml |
COMPOSITION
1 ml of product contains following active substances (mg):
Iron trivalent (in the complex compound of iron (III) hydroxide with Dextran of low molecular weight) – 100.0 mg;
Cyanocobalamin – 5.0 μg;
Folic acid – 200.0 μg
Excipients: Phenol, water for injection.
PHARMACOLOGICAL PROPERTIES
FERRUM + is a complex anti-anemia agent that increases the level of hemoglobin. Product replenishes iron reserves, activates the synthesis of hemoglobin and hematopoiesis processes, and increases the resistance of the body. Iron is a part of more than 70 compounds: hemoglobin, myoglobin, cytochromes, catalase, peroxidase, transferrin, ferritin, etc. They perform the following functions in the body: transportation and deposition of oxygen to tissues; transfer of electrons in the processes of tissue respiration, transport and deposition of iron (ferritin, transferrin, hemosiderin, etc.); participation in oxidation-reduction reactions.
Iron (in a complex compound with dextran of low molecular weight) through specific receptors on the membranes of proliferating erythroid cells enters the cell. Iron dextran is absorbed into the blood from the injection site, is transferred by transferrin to the depot: liver and spleen cells, reticuloendothelial system, bone marrow, and gradually consumed for the needs of the body.
Vitamin B12 (cyanocobalamin) stimulates erythrocytopoiesis, affecting the conversion of folic acid to tetrahydrofolic, which accelerates the maturation of erythrocytes, the synthesis of hepatoprotectors – methionine and choline, stimulates the protein-synthesizing function of the liver, assimilation of carotene and synthesis of retinol, conversion of propionic acid to glucose. It binds to proteins by 90%; the time to reach the maximum concentration after subcutaneous and intramuscular injection is 1 hour. Excreted by the kidneys and in bile. Penetrates through the placental barrier.
Folic acid refers to the vitamins of group B, takes part in hemopoiesis, synthesis of amino acids, pyrimidines and purines of nucleic acids, and in exchange of choline. In combination with vitamin B12 (cyanocobalamin) stimulates the process of hematopoiesis. With a lack of folic acid, macrocytic hypochromic anemia develops, the quality of wool worsens in animals, the young birds is poorly covered with a feathers, the feathers are depigmented, and signs of perosis are observed.
TARGET ANIMALS
Cattle, goats, sheep, dogs.
INDICATIONS
For the treatment of calves, lambs, kids, dogs, fur-bearing animals with iron deficiency anaemia and for the prevention of disease, in case of haemorrhage and haemorrhagic diathesis.
ROUTES OF ADMINISTRATION AND DOSAGES
Product is injected intramuscularly into the thigh or neck area:
Type of animals (per animal)
If necessary, the product is given to the young growth repeatedly after 10-12 days in the same doses.
WITHDRAWAL PERIOD
0 days.
SHELF LIFE
24 months.
Shelf life after first opening: 14 days if stored in dry, dark places, out of the reach of children at 5° to 25° С.
STORAGE CONDITIONS
Store in dry, dark places, out of the reach of children at 5° to 25° С.
1 ml of product contains following active substances (mg):
Iron trivalent (in the complex compound of iron (III) hydroxide with Dextran of low molecular weight) – 100.0 mg;
Cyanocobalamin – 5.0 μg;
Folic acid – 200.0 μg
Excipients: Phenol, water for injection.
PHARMACOLOGICAL PROPERTIES
FERRUM + is a complex anti-anemia agent that increases the level of hemoglobin. Product replenishes iron reserves, activates the synthesis of hemoglobin and hematopoiesis processes, and increases the resistance of the body. Iron is a part of more than 70 compounds: hemoglobin, myoglobin, cytochromes, catalase, peroxidase, transferrin, ferritin, etc. They perform the following functions in the body: transportation and deposition of oxygen to tissues; transfer of electrons in the processes of tissue respiration, transport and deposition of iron (ferritin, transferrin, hemosiderin, etc.); participation in oxidation-reduction reactions.
Iron (in a complex compound with dextran of low molecular weight) through specific receptors on the membranes of proliferating erythroid cells enters the cell. Iron dextran is absorbed into the blood from the injection site, is transferred by transferrin to the depot: liver and spleen cells, reticuloendothelial system, bone marrow, and gradually consumed for the needs of the body.
Vitamin B12 (cyanocobalamin) stimulates erythrocytopoiesis, affecting the conversion of folic acid to tetrahydrofolic, which accelerates the maturation of erythrocytes, the synthesis of hepatoprotectors – methionine and choline, stimulates the protein-synthesizing function of the liver, assimilation of carotene and synthesis of retinol, conversion of propionic acid to glucose. It binds to proteins by 90%; the time to reach the maximum concentration after subcutaneous and intramuscular injection is 1 hour. Excreted by the kidneys and in bile. Penetrates through the placental barrier.
Folic acid refers to the vitamins of group B, takes part in hemopoiesis, synthesis of amino acids, pyrimidines and purines of nucleic acids, and in exchange of choline. In combination with vitamin B12 (cyanocobalamin) stimulates the process of hematopoiesis. With a lack of folic acid, macrocytic hypochromic anemia develops, the quality of wool worsens in animals, the young birds is poorly covered with a feathers, the feathers are depigmented, and signs of perosis are observed.
TARGET ANIMALS
Cattle, goats, sheep, dogs.
INDICATIONS
For the treatment of calves, lambs, kids, dogs, fur-bearing animals with iron deficiency anaemia and for the prevention of disease, in case of haemorrhage and haemorrhagic diathesis.
ROUTES OF ADMINISTRATION AND DOSAGES
Product is injected intramuscularly into the thigh or neck area:
Type of animals (per animal)
Prevention, ml | Treatment (starting from 2-weeks of age), ml | |
Piglets | 1,0-1,5 at 3-5 days of life | 2,0 |
Sows | 8-10 20-15 days before farrowing | - |
Calves | 4,0-5,0 at 3-4 days of life | 6,0 - 7,0 |
Lambs | 1,0 at 5-6 days of life | 1,5 - 2,0 |
Dogs, fur-bearing animals (per body weight) | ||
Weight, kg | Prevention, ml | Treatment, ml |
up to 2,5 | - | 0,5 |
2,5 - 10 | - | 1,0 |
more 10 | - | 2,0 |
If necessary, the product is given to the young growth repeatedly after 10-12 days in the same doses.
WITHDRAWAL PERIOD
0 days.
SHELF LIFE
24 months.
Shelf life after first opening: 14 days if stored in dry, dark places, out of the reach of children at 5° to 25° С.
STORAGE CONDITIONS
Store in dry, dark places, out of the reach of children at 5° to 25° С.